Doctor-reviewed articles

Health Articles

Doctor-reviewed health articles from YOUNIFY Clinic covering weight management, GLP-1 medications, upper endoscopy, fatty liver disease, and knee pain. Written in plain language so patients can prepare better questions for their doctor.

Stomach and weight
Weight regain after sleeve gastrectomy
Weight-loss medicine
GLP-1 before upper endoscopy
Liver and metabolism
GLP-1 for MASH / fatty liver inflammation
Knee pain
Knee pain and osteoarthritis guides
Endoscopy room image representing stomach evaluation after weight-loss surgery
Weight Management8 min readUpdated April 28, 2026

Weight Regain After Sleeve Gastrectomy: Endoscopic Revision vs Revisional Surgery

A patient-friendly summary of Dr. Noppachai Siranart's research on recurrent weight gain after sleeve gastrectomy and how endoscopic sleeve-in-sleeve compares with surgical revision.

  • Weight regain after sleeve gastrectomy can happen and does not always mean the patient has failed. It may involve sleeve dilation, appetite biology, eating pattern, sleep, stress, medication, and other health factors.
  • In this study, 164 matched patients were compared. Endoscopic sleeve-in-sleeve revision showed similar weight loss to surgical revision at 6 and 12 months.
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Upper endoscopy image representing GLP-1 medication safety before gastroscopy
Weight Medication7 min readUpdated April 28, 2026

Do GLP-1 Weight-Loss Medications Need to Be Stopped Before Upper Endoscopy?

A patient-friendly summary of Dr. Noppachai Siranart's research on GLP-1 receptor agonists, gastric emptying, and upper endoscopy safety.

  • GLP-1 medications such as semaglutide, liraglutide, dulaglutide, and tirzepatide can support weight loss and diabetes care, but they may slow stomach emptying in some people.
  • In 629 patients taking GLP-1 medications who underwent upper endoscopy, continuing the medication was not clearly associated with more retained stomach contents, early procedure termination, or aspiration events.
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Doctor discussing metabolic health results related to fatty liver disease
Weight Medication8 min readUpdated April 28, 2026

Can GLP-1 Weight-Loss Medications Help MASH Fatty Liver?

A clear summary of Dr. Noppachai Siranart's meta-analysis on GLP-1 receptor agonists and biopsy-confirmed MASH.

  • MASH is fatty liver disease with inflammation and liver cell injury. It is more common in people with obesity, type 2 diabetes, and metabolic risk factors.
  • This meta-analysis included 6 randomized trials with 1,555 patients and found GLP-1 medications were associated with higher MASH resolution without worsening fibrosis compared with placebo.
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Doctor assessing knee pain with a patient in a consultation room
Knee Pain12 min readUpdated April 27, 2026

Where Should Knee Pain Be Treated? Causes, Treatments, and Non-Surgical Options

A detailed guide to knee pain: common causes, warning signs, physical therapy, injections, PRP, and GAE as a non-surgical option for selected patients.

  • Knee pain can come from osteoarthritis, tendon or muscle inflammation, meniscus or ligament injury, repeated loading, body weight, or inflammation around the joint.
  • A medical assessment is recommended if knee pain lasts longer than 1-2 months, affects walking or stairs, keeps recurring after physical therapy, injections, or PRP, or comes with swelling, redness, warmth, or inability to bear weight.
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Patient being assessed for knee pain while walking in a rehabilitation area
Knee Pain6 min readUpdated April 27, 2026

Knee Pain When Walking: Causes, Warning Signs, and What to Do

Knee pain during walking, stairs, or longer activity may relate to osteoarthritis, muscle imbalance, meniscus problems, or overuse.

  • Knee pain while walking is often related to repeated joint load, weak muscles around the knee, osteoarthritis, or meniscus and ligament injury.
  • Pain that increases with distance, stairs, or sit-to-stand movement should be assessed with walking pattern, hip and thigh strength, and knee condition in mind.
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Inner knee pain location being assessed during a clinical examination
Knee Pain6 min readUpdated April 27, 2026

Inner Knee Pain: Meniscus, Osteoarthritis, Ligament, or Tendon Irritation?

Inner knee pain may involve medial compartment osteoarthritis, medial meniscus injury, MCL irritation, or tendons and bursae around the knee.

  • Inner knee pain can come from medial compartment osteoarthritis, medial meniscus injury, MCL injury, or irritation of tendons and bursae around the knee.
  • Locking, swelling after twisting, or knee instability should be assessed to check joint structures.
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Doctor explaining knee osteoarthritis with a knee joint model
Knee Osteoarthritis7 min readUpdated April 27, 2026

Knee Osteoarthritis: Symptoms, Stages, and Options Before Surgery

A clear guide to knee osteoarthritis, from symptoms and staging to non-surgical care, injections, GAE, and when surgery may be considered.

  • Knee osteoarthritis is a condition involving cartilage and other joint structures, leading to pain, stiffness, swelling, or reduced movement.
  • Treatment depends on stage and patient goals, starting with targeted exercise, weight and load management, medication, injections, and minimally invasive procedures in selected cases.
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